Table 6 Mother−child compatibility at minor histocompatibility antigens (mHag) and risk of systemic lupus erythematosus (SLE) among mothers with the corresponding HLA restriction

From: Mother−child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers

Any mHag-matched children

HLA restriction

SLE

n (%)

Controls

n (%)

OR (95% CI)a

p

SLC19A1

DRB1*15:01

    

None

24 (52)

111 (53)

Reference

 

1 or more

22 (48)

98 (47)

0.9 (0.5–1.7)

0.76

LB-WNK1

A*02:01

    

None

45 (47)

252 (57)

Reference

 

1 or more

50 (53)

188 (43)

1.5 (0.9–2.3)

0.11

HA-3

A*01:01

    

None

32 (48)

152 (52)

Reference

 

1 or more

34 (52)

140 (48)

1.2 (0.7–2.1)

0.50

ZAPHIR

B*07:02

    

None

29 (74)

117 (52)

Reference

 

1 or more

10 (26)

106 (48)

0.4 (0.2–0.8)

0.01

HEATR1

B*08:01

    

None

31 (54)

127 (64)

Reference

 

1 or more

26 (46)

73 (37)

1.5 (0.8–2.7)

0.22

C19orf48

A*02:01

    

None

44 (46)

245 (56)

Reference

 

1 or more

51 (54)

195 (44)

1.4 (0.9–2.3)

0.13

  1. OR odds ratio, 95% CI confidence interval
  2. aAdjusted for number of live births