Table 6 Mother−child compatibility at minor histocompatibility antigens (mHag) and risk of systemic lupus erythematosus (SLE) among mothers with the corresponding HLA restriction
Any mHag-matched children | HLA restriction | SLE n (%) | Controls n (%) | OR (95% CI)a | p |
---|---|---|---|---|---|
SLC19A1 | DRB1*15:01 | ||||
None | 24 (52) | 111 (53) | Reference | ||
1 or more | 22 (48) | 98 (47) | 0.9 (0.5–1.7) | 0.76 | |
LB-WNK1 | A*02:01 | ||||
None | 45 (47) | 252 (57) | Reference | ||
1 or more | 50 (53) | 188 (43) | 1.5 (0.9–2.3) | 0.11 | |
HA-3 | A*01:01 | ||||
None | 32 (48) | 152 (52) | Reference | ||
1 or more | 34 (52) | 140 (48) | 1.2 (0.7–2.1) | 0.50 | |
ZAPHIR | B*07:02 | ||||
None | 29 (74) | 117 (52) | Reference | ||
1 or more | 10 (26) | 106 (48) | 0.4 (0.2–0.8) | 0.01 | |
HEATR1 | B*08:01 | ||||
None | 31 (54) | 127 (64) | Reference | ||
1 or more | 26 (46) | 73 (37) | 1.5 (0.8–2.7) | 0.22 | |
C19orf48 | A*02:01 | ||||
None | 44 (46) | 245 (56) | Reference | ||
1 or more | 51 (54) | 195 (44) | 1.4 (0.9–2.3) | 0.13 |