Table 7 Fisher’s Exact test between having any children who are mHag and HLA compatible and risk of systemic lupus erythematosus (SLE) among mothers (histocompatible from the mother’s perspective at the restriction HLA locus and at the minor histocompatibility antigen)
Any HLA-matched/mHag-matched children | HLA restriction | SLE n (%) | Controls n (%) | pa |
---|---|---|---|---|
SLC19A1 | DRB1*15:01 | |||
None | 44 (96) | 189 (90) | ||
1 or more | 2 (4) | 20 (10) | 0.39 | |
LB-WNK1 | A*02:01 | |||
None | 73 (77) | 384 (87) | ||
1 or more | 22 (23) | 56 (13) | 0.02 | |
HA-3 | A*01:01 | |||
None | 57 (86) | 251 (86) | ||
1 or more | 9 (14) | 41 (14) | 1.0 | |
ZAPHIR | B*07:02 | |||
None | 39 (100) | 202 (91) | ||
1 or more | 0 (0) | 21 (9) | 0.05 | |
HEATR1 | B*08:01 | |||
None | 51 (89) | 189 (95) | ||
1 or more | 6 (11) | 11 (5) | 0.22 | |
C19orf48 | A*02:01 | |||
None | 75 (79) | 366 (83) | ||
1 or more | 20 (21) | 74 (17) | 0.37 |