Fig. 2: Features of exome sequencing (ES)-derived candidate variants, and association with Sanger confirmation status. | Genetics in Medicine

Fig. 2: Features of exome sequencing (ES)-derived candidate variants, and association with Sanger confirmation status.

From: Development of an evidence-based algorithm that optimizes sensitivity and specificity in ES-based diagnostics of a clinically heterogeneous patient population

Fig. 2

Stippled gray lines indicate the corresponding values for all 1,048 variants. a Analogous features. Significance of differences between means (+/- SEM) was calculated using the two-sided Student’s t-test. b Digital features. Significance of differences was calculated using Fisher’s exact test

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