Table 4 Patients meeting NF2 criteria after therapeutic radiotherapy aged <20 years
Patient ID | Age radiotherapy (in 5-year age group) | Indication | Sites | NF2 criteria | Delay to criteria being met in years | Tumor NF2 analysis | Lymphocyte NF2 analysis |
---|---|---|---|---|---|---|---|
9803462 | 15–19 | VS | Brain | Bilateral VS | 12 | - | Nil found |
937087 | 0–4 | Neuroblastoma | Brain & spine | Unilateral VS + 2 spinal schwannoma | 25 | Nil found | Nil found |
157731 | 15–19 | Lymphoreticular malignancy | Brain & spine | Unilateral VS + 2 schwannoma | 22 | c.1574+1G>A + LOH | Nil found |
9869906 | 5–9 | Neurogenic tumor unrelated to NF2 | Brain | Left VS, trigeminal schwannoma, C4 schwannoma | 22 | - | Nil found |
9000765 | 0–4 | Lymphoreticular malignancy | Brain & spine | Unilateral VS + 2 meningiomas C3/4 schwannoma | 25 | - | Nil found |
9116 | 5–9 | Meningioma | Brain | Bilateral VS | 2 | - | c.241-9A>G |