Table 2 Sensitivity: projection length ($AU) and annual discount rates
5% Annual discount | ICER at 20 years | ICER at 30 years | ICER at 40 years | ICER at 50 years | ICER at 60 years |
---|---|---|---|---|---|
Model 1: cohort | $31,144.35 | $25,638.73 | $23,291.17 | $22,112.50 | $21,477.44 |
Model 2: cohort and first-degree relative cascade testing | $20,839.57 | $15,681.53 | $13,783.00 | $12,895.54 | $12,431.37 |
Model 3: cohort, first-degree relative cascade testing, and parental reproductive outcomes | $14,235.28 | $11,455.57 | $10,377.60 | $9866.80 | $9615.91 |
3.5% Annual discount | ICER at 20 years | ICER at 30 years | ICER at 40 years | ICER at 50 years | ICER at 60 years |
Model 1: cohort | $27,933.72 | $22,248.14 | $19,689.89 | $18,311.83 | $17,503.08 |
Model 2: cohort and first-degree relative cascade testing | $18,188.31 | $13,162.53 | $11,234.11 | $10,274.10 | $9729.03 |
Model 3: cohort, first-degree relative cascade testing, and parental reproductive outcomes | $12,796.23 | $9958.90 | $8809.62 | $8227.69 | $7921.78 |
0% Annual discount | ICER at 20 years | ICER at 30 years | ICER at 40 years | ICER at 50 years | ICER at 60 years |
Model 1: cohort | $21,397.07 | $15,679.05 | $12,957.44 | $11,377.03 | $10,356.12 |
Model 2: cohort and first-degree relative cascade testing | $13,077.13 | $8641.12 | $6877.60 | $5940.66 | $5353.31 |
Model 3: cohort, first-degree relative cascade testing, and parental reproductive outcomes | $9847.65 | $7069.60 | $5914.35 | $5290.70 | $4962.49 |