Fig. 1: Phenotypic traits of patients with Saul–Wilson syndrome.
From: Defining the clinical phenotype of Saul–Wilson syndrome
(a–d) Progeroid features seen in the first few months of life: (a) P2.1, (b) P5.1, (c) P6.1, (d) P7.1. In addition, wrist contractures can be seen in (a), blue sclerae in (a) and (d), and boots and bar treatment for clubfoot in (c). (e–h) Facial features seen during early childhood: (e) P1.1, (f) P5.1, (g) P6.1, (h) P10.1. Note prominent, round forehead with prominent scalp veins in all. (i–l) Facial features seen in late childhood: (i) P7.1, (j) P5.1, (k) P6.1, (l) P10.1. The forehead is still prominent, but mainly tall rather than round. (m,n) Facial features in adolescence: (m) P2.1, (n) P7.1. (o, p) Facial features in adulthood (o) P2.1, (p) P7.1. (q–t) Feet in P1.1 at 4 years old (q), P9.1 at 9 years old (r), P7.1 at 27 years old (s), and P2.1 at 29 years old (t). Note short distal phalanges in all, and metatarsus varus in (q). (u–x) Hands in P1.1 at 4 years old (u), P4.1 at 5 years old (v), P9.1 at 9 years old (w), and P7.1 at 27 years old (x). Note short distal phalanges of variable degree in all.
