Fig. 1: Frequency of germline variants in an unselected cohort of 294 metastatic renal cell carcinoma (RCC) patients.
From: Prevalence of pathogenic germline variants in patients with metastatic renal cell carcinoma

(a) Number of patients with a germline variant in RCC predisposition gene (dark gray) or other cancer-related gene (light gray). (b) Percentage of mutated patients depicted by gene type in common RCC histologies: clear cell (ccRCC, n = 226), papillary (pRCC, n = 25) and chromophobe (chRCC, n = 15). The number of mutated patients is expressed in parentheses for each gene.