Fig. 1: Distribution of KLRC2 and HLA-E variants in patients with different disease severities of COVID-19.

Distribution of KLRC2 (a,c) or HLA-E (b,c) variants, between control persons (N = 260), nonhospitalized (N = 92), hospitalized non-ICU (N = 190) as well as hospitalized ICU (N = 79) COVID-19 patients. Bars represent the relative frequency of (a) KLRC2wt/wt, KLRC2wt/del, and KLRC2del/del; (b) HLA-E*0101/0101, HLA-E*0101/0103, and HLA-E*0103/0103; (c) combined KLRC2wt/wt or KLRC2del as well as the HLA-E*0103/0103 or HLA-E*0101 variants for each group. χ2 test was used for statistical comparison between variants. del deletion, ICU intensive care unit, wt wild type.