Fig. 3: Activation of genes regulating pyrophosphate (PPi) in human plexiform neurofibromas (NFs).
From: A molecular basis for neurofibroma-associated skeletal manifestations in NF1
(a) Gene expression in cultured Schwann cells (SCs) from NFs of individuals with neurofibromatosis type 1 (NF1) (n = 24) versus cultured embryonic Schwann cell controls (n = 7) (RNAseq). (b, c) Gene expression in human NF1 NF tissue (n = 13) versus normal sciatic nerve control tissue (n = 3) (microarray). *p < 0.05; ***p < 0.001 by two-sided t-test.
