Table 2 Total cohort screening history.

From: Tumor detection rates in screening of individuals with SDHx-related hereditary paraganglioma–pheochromocytoma syndrome

 

HCI

U of M

Penn

Total

Total cohort

  Total subjects (n)

100

95

68

263

  Imaging screens (n)

180

186

125

491

  Screens per subject (mean ± SD)

1.80 ± 1.17

1.96 ± 1.24

1.84 ± 1.23

1.87 ± 1.22

  Range screens per subject (n)

1–6

1–6

1–7

1–7

  Screens including biochemistry (n [% screens])

117 (65%)

135 (73%)

91 (73%)

343 (70%)

  Follow-up time, years (mean ± SD)

1.58 ± 2.42

2.04 ± 2.69

1.82 ± 3.22

1.81 ± 2.75

 Subjects with ≥2 screens (n [%])

44 (44%)

47 (49%)

32 (47%)

123 (47%)

 Follow-up time, years (mean ± SD)

3.60 ± 2.47

4.13 ± 2.45

3.86 ± 3.75

3.87 ± 2.86

 Subjects with ≥3 screens (n [%])

20 (20%)

24 (25%)

15 (22%)

59 (22%)

 Follow-up time, years (mean ± SD)

5.22 ± 2.21

5.72 ± 2.34

5.53 ± 4.91

5.50 ± 3.17

No prior history of PGL/PCC

  Subjects (n [% of total subjects])

83

59

52

194 (74%)

  Imaging screens (n [% of total screens])

149

98

87

334 (68%)

Prior history of PGL/PCC

  Subjects (n [% of total total])

17

36

16

69 (26%)

  Imaging screens (n [% of total screens])

31

88

38

157 (32%)

  1. HCI Huntsman Cancer Institute, PCC pheochromocytomas, Penn University of Pennsylvania, PGL paragangliomas, U of M University of Michigan.