Table 4 Cost differences between cohorts: total cost, mean cost per patient, and cost savings from GS.

From: A cost-effectiveness analysis of genomic sequencing in a prospective versus historical cohort of complex pediatric patients

Cohort and investigation method

Total cost ($AU)

Mean cost per person ($AU) and SD

Mean cost saving per person from GS ($AU)

Historical cohort

796,667.93

8755 SD 5298

Prospective cohort (investigations excluding GS)

265,540.70

Prospective cohort (including singleton GS at AU$3100 and segregation costs)

556,240.70

5205 SD 1680

3602 95% CI 2520–4685

Prospective cohort (including trio GS at AU$3500)

587,540.70

6305 SD 1680

2446 95% CI 1380–3515

  1. CI confidence interval, GS genome sequencing.