Fig. 1: Workflow highlighting the steps in the expert curation process to resolve conflicting interpretations or variants of uncertain significance.
From: Disease-specific ACMG/AMP guidelines improve sequence variant interpretation for hearing loss

Refer to “Materials and Methods” for a detailed description of the curation process. ACMG/AMP American College of Medical Genetics and Genomics/Association for Molecular Pathology, HL hearing loss, VCEP Variant Curation Expert Panel.