Fig. 5: Among genes with high Neutrality Index (NI), those with a high frequency of loss-of-function alleles are enriched for non-synonymous polymorphism (Pn). | Heredity

Fig. 5: Among genes with high Neutrality Index (NI), those with a high frequency of loss-of-function alleles are enriched for non-synonymous polymorphism (Pn).

From: The population genomics of adaptive loss of function

Fig. 5

Shown here are mean components of NI in A. thaliana genes with high (top 20%) NI values in relation to loss-of-function (LoF) allele frequencies (binned by quartiles). Loss-of-function calls based on approach from (Monroe et al. 2018; Baggs et al. 2020) and data from (Monroe et al. 2020). Pn = non-synonymous polymorphism, Ps = synonymous polymorphism, Dn = non-synonymous divergence, Ds = synonymous divergence (using A. lyrata as an outgroup).

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