Table 1 Recent whole genome re-sequencing projects with functional annotations of variants. Numbers of premature stop, synonymous, and non-synonymous single nucleotide polymorphisms indicate number of variants segregating among the genotypes sequenced (Fig. 2). Sample Size = number of genotypes sequenced.

Ananas comosus

89

7,084

689,019

589,484

(Chen et al. 2019)

Arabidopsis thaliana

1,135

27,813

803,665

1,135,115

(1001 Genomes Consortium 2016)

Bos indicus

20

1,132

255,296

155,251

(Iqbal et al. 2019)

Bos taurus

15

3,837

1,155,244

524,103

(Zhang et al. 2019)

Branchiostoma belcheri

20

11,487

2,818,189

1,467,863

(Bi et al. 2020)

Brassica napus

991

1,413

120,926

79,018

(Wu et al. 2019)

Caenorhabditis elegans

330

5,084

271,950

261,538

(Cook et al. 2017)

Cairina moschata

15

285

36,517

19,817

(Gu et al. 2020)

Canis lupus

722

11,273

540,063

332,559

(Plassais et al. 2019)

Capsella grandiflora

15

5,209

644,326

478,238

(Koenig et al. 2019)

Capsella orientalis

16

269

11,250

13,281

(Koenig et al. 2019)

Capsella rubella

50

2,508

194,078

171,071

(Koenig et al. 2019)

Cicer arietinum

16

352

50,290

38,078

(Thudi et al. 2016)

Cucumis melo

1,175

7,030

102,687

94,426

(Zhao et al. 2019)

Cucurbita pepo

7

864

156,828

111,687

(Xanthopoulou et al. 2019)

Drosophila melanogaster

205

1,532

351,255

182,520

(Huang et al. 2014)

Ebola virus

140

3

555

403

(Ladner et al. 2015)

Echinochloa crus-galli

328

9,264

184,746

319,816

(Ye et al. 2019)

Felis catus

54

838

128,844

77,662

(Buckley et al. 2020)

Fraxinus excelsior

37

2,997

251,249

259,946

(Sollars et al. 2017)

Glycine max

1,007

2,826

122,469

182,479

(Torkamaneh et al. 2019)

Gossypium spp.

243

6,851

101,059

128,512

(Du et al. 2018)

Hippotragus niger

7

201

11,350

11,386

(Koepfli et al. 2019)

Homo sapiens

141,465

133,019

2,173,110

4,548,307

(Karczewski et al. 2020)

Macaca mulatta

133

2,642

148,278

126,445

(Xue et al. 2016)

Manihot esculenta

203

4,399

265,094

299,197

(Ramu et al. 2017)

Mycoplasma pneumoniae

15

88

4,382

6,891

(Xiao et al. 2015)

Oryza sativa

3,024

198,609

2,952,705

3,599,083

Wang et al. 2018)

Parastagonospora nodorum

197

2,815

226,803

160,159

(Richards et al. 2019)

Phaseolus vulgaris

683

1,352

112,173

97,536

(Wu et al. 2020)

Populus trichocarpa

1,014

8,365

231,894

333,036

(Piot et al. 2019)

Protobothrops mucrosquamatus

22

883

53,023

56,553

(Aird et al. 2017)

Puccinia hordei

5

2,629

46,763

67,526

(Chen et al. 2019)

Rattus norvegicus

40

285

42,182

26,239

(Hermsen et al. 2015)

SARS-nCoV-2

8,053

90

2,678

4,731

(Rayko and Komissarov 2020)

Saccharomyces cerevisiae

1,011

7,207

517,729

549,300

(Peter et al. 2018)

Solanum melongena

7

438

6,645

12,828

(Gramazio et al. 2019)

Solanum tuberosum

201

4,962

541,208

515,492

(Li et al. 2018)

Sorghum bicolor

44

3,114

112,255

112,108

(Mace et al. 2013)

Trypanosoma evansi

15

1,685

30,714

53,002

(Lazaro et al. 2020)