Table 4 Genes flanking the most important genome-wide associated SNPs within each chromosome for TiLV resistance.

From: A major quantitative trait locus affecting resistance to Tilapia lake virus in farmed Nile tilapia (Oreochromis niloticus)

Onia

Trait

QTL regionb

Gene names

Left position

Right position

03

BS

71,347,333

72,347,333

zbed1c, kcnab1, trappc1, nlrc3, psmb6, pigr, nlrc3, mrc1, ephb4, fcgr2b, agp4, btnl2, btnl10

22

BS and TD

1

755,104

zhx1, lgals17, vps52, hmcn1, senp1, muc5ac, ha1f, rnf2, atad2, rps18, ptk7

22

BS

1,439,192

2,439,192

zbed1, zscan2, tmem65, sema6d, scgn, tatdn1, pomc, NADH, mtss1, grik5, fibcd1, carmil1, rnf139, ceacam5, atx2

22

BS

1

739,073

zhx1, igals17, vps52, hmcn1, senp1, muc5ac, ha1f, rnf2, atad2, rps18, ptk7

22

BS and TD

4,879,664

5,879,664

cacgn7, cacgn6, cacgn4, vamp2, styk1, trim29, tpi1, glut1, phc1, iffo2, gnb3, gapdh, gtan, eno2, g2e3, trim21, cox6b1, chd4, clcn1, cdc42, cd209e, clec6a

  1. aNumber of chromosome on the Oreochromis niloticus genome.
  2. bQTL region size was defined as 500 kb upstream and downstream from the SNP location.
  3. cIn bold the name of the genes with a role known to be involved in a viral infection process.
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