Fig. 7: Proposed model for the function of LsAP2 during leaf development in lettuce.

LsAP2 uses its EAR motif to recruit TPL/TPR corepressors and regulates lettuce leaf development via two pathways. LsAP2 may regulate leaf morphology by physically interacting with CIN-like TCPs and inhibiting their activity. LsAP2 may also regulate leaf polarity by directly binding to the promoter of LsKAN2 and repressing its expression. Arrows, positive regulation; bars, negative regulation