Fig. 1: Sequential changes in MRI.
From: Mitochondrial DNA 3243A>T mutation in a patient with MELAS syndrome

(a) Brain MRI on admission shows small multifocal gray matter regions in the right temporal, parietal, and occipital lobes, and diffuse white matter lesions in the left temporal lobe, visualized as high-intensity areas in FLAIR images (left). White matter lesions in the left temporal lobe show low intensity in diffusion-weighted images (right). b Extended white matter and left thalamic lesions appeared after a stroke-like episode