Fig. 2
From: eLD: entropy-based linkage disequilibrium index between multiallelic sites
Pairwise quantification of LD among the classical HLA gene variants. Pairwise LD index of ε among the 4-digit alleles of the classical HLA genes were evaluated using eLD. Phased HLA alleles were obtained from a subset of the East Asian subjects (n = 300) of the original studies6, 7. Strong LD between HLA-C and HLA-B, among HLA-DRB1, HLA-DQA1, and HLA-DQB1, and between HLA-DPA1 and HLA-DPB1 was observed (ε > 0.15)
