Table 2 GWASs of narcolepsy type 1 (NT1)
From: Genetics of narcolepsy
Chr | rs number | Gene | Effect allele | Minimum P-value | Odds ratio (95% CI) | Study population |
|---|---|---|---|---|---|---|
1 | rs7553711 | TNFSF4 | C | 4 × 10−8 | 1.3 (1.2–1.5) | European57 |
3 | rs3181077 | CCR1/CCR3 | T | 6 × 10−6 | 1.6 (1.3–2.0) | Japanese59 |
7 | rs2854536 | TCRB | G | 4 × 10−8 | 0.78 (0.71–0.85)a | Chinese and European58 |
10 | rs10995245 | ZNF365 | A | 1 × 10−11 | 1.2 (1.2–1.3)a | Chinese and European58 |
14 | rs1154155 | TCRA | C | 3 × 10−22 | 1.5 (1.3–1.8) −1.9 (1.6–2.2) | Chinese, European, Japanese, and Korean55 |
15 | rs34593439 | CTSH | A | 2 × 10−8 | 1.3 (1.2–1.5) | European57 |
19 | rs2305795 | P2RY11 | A | 6 × 10−10 | 1.3 (1.2–1.4)a | Chinese, European, Japanese, and Korean56 |
21 | rs2834188 | IL10RB-IFNAR1 | A | 2 × 10−8 | 0.77 (0.71–0.85)a | Chinese and European58 |
22 | rs5770917 | CPT1B | C | 4 × 10−7 | 1.4 (1.0–2.0) −1.8 (1.4–2.3) | Japanese and Korean48 |
