Fig. 1: Overview of the TogoVar web interface.
From: TogoVar: A comprehensive Japanese genetic variation database
a Simple search. a-1 Switch the reference sequence. a-2 Text box for keyword search. Users can enter the following keywords: (1) position or range in the GRCh37 reference genome of a target variant, (2) dbSNP rs number, (3) TogoVar ID, (4) gene symbol including aliases, or (5) disease name (ClinVar condition). a-3 Statistics/filters pane. Users can narrow down the search result by (1) dataset name, (2) alternative allele frequency, (3) type of variant (SNV, indel, etc.), (4) variant calling quality, and (5) clinical significance. The number of variants per facet is displayed. a-4 Preview pane for the variant selected in the result table. b Report pages. b-1 Variant report page. b-2 Gene report page. b-3 Disease report page. c Advanced search, showing search criteria for variants that have a GEM-J WGA or ToMMo 8.3KJPN allele frequency of 0.3 or higher and a gnomAD non-Finnish European allele frequency of 0.01 or lower and are pathogenic or likely pathogenic.
