Fig. 2: The deleted exon and structure of BARD1.
From: BARD1 deletion in a patient with suspected hereditary colorectal cancer
A The results of the copy number analysis of BARD1 detected by the 84-gene MGPT. The red arrow indicates the deletion of BARD1 exon 3. B Structure of BARD1. Exon structure, coding exons (gray area), and domain composition of full-length BARD1 based on NM_000465.4 (green arrow) and NP_000456.2 (red arrow), with scales at the nucleotide (bp) and amino acid (aa) levels. BARD1 has an N-terminal RING-finger domain (RING), three centrally located ankyrin repeats (ANK), and two C-terminal BRCT (BRCA1 C-terminus) domains (BRCT1 and BRCT2).
