Table 2 Hazard ratios for stroke events according to the risk categories of blood pressure and glucose in diabetic population

From: Burden of high blood pressure as a contributing factor to stroke in the Japanese community-based diabetic population

 

No. of subjects

No. of events

No./1,000 person years

Sex and age adjusted HR and 95% CI

P value

P for trend

Multivariable-adjusted HRa and 95% CI

P value

P for trend

Blood pressure category

      

0.001

   

0.001

 Normotension

397

13

3.8

1.00

   

1.00

   

 Prehypertension

580

38

7.9

1.86

0.99–3.50

0.054

 

1.85

0.98–3.50

0.056

 

 Hypertension

629

68

13.4

2.94

1.62–5.34

0.000

 

2.87

1.57–5.26

0.001

 

HbA1c category

      

0.409

   

0.430

 <7.0%

876

65

9.0

1.00

   

1.00

   

 7.0%–7.9%

393

27

8.1

0.97

0.62–1.52

0.884

 

0.98

0.63–1.55

0.945

 

 ≥8.0%

337

27

9.8

1.33

0.84–2.09

0.220

 

1.33

0.84–2.12

0.224

 
  1. HR hazard ratio, CI confidence interval
  2. aHazard ratio in a multivariable Cox proportional hazards model including age, sex, body mass index, estimated glomerular filtration rate, dyslipidemia (yes or no), smoking habits (yes or no), and anti-hypertensive and anti-diabetic medications (yes or no)