Fig. 4
From: Modulation of sympathetic preganglionic neuron activity via adrenergic receptors

The responses of a firing-SPN to NE in the presence of TTX. a Depolarization of the firing-SPN accompanying the generation of spontaneous (probably calcium) action potentials from 3 to 4 min after the start of the 1 μM NE. b Another firing-SPN was hyperpolarized 3–4 min after the superfusion of 1 μM NE. The application of 10 pA (in a) or 10 pA (in b) hyperpolarizing square current pulses elicits negative deflections of the baseline membrane potential in proportion to the input resistance. Note that NE application brought about an increase of input resistance in (a) and decrease of input resistance in (b)