Fig. 2

Relative mRNA expression of ATP2B1, ATP2B4, TRPV6 and renin in the kidney, and urine 8-OHdG creatinine ratio. Relative mRNA expression levels of (a) ATP2B1, b ATP2B4, TRPV6 and renin were determined in the kidney of ATP2B1+/+ and ATP2B1+/− mice (n = 6 for each group). ATP2B1 mRNA expression was decreased in the kidney of ATP2B1+/− mice. The mRNA expression of ATP2B4, TRPV6 and renin was not different between the two groups. Urine 8-OHdG and creatinine were measured in ATP2B1+/− (n = 11) and ATP2B1+/+ mice (n = 10). Urine 8-OHdG creatinine ratio was not different between the two groups