Table 2 Multivariate regression analysis of serum ADMA level

From: Urinary sodium-to-potassium ratio and serum asymmetric dimethylarginine levels in patients with type 2 diabetes

 

Age- and sex-adjusted model

Multivariate modela

 

Adjusted β (95% CI)

P

Adjusted β (95% CI)

P

Urinary sodium-to-potassium ratio

Overall (n = 243)

0.123 (0.000 to 0.007)

0.058

0.104 (−0.002 to 0.016)

0.115

  Non-obese (n = 121)

0.265 (0.007 to 0.033)

0.003

0.238 (0.004 to 0.032)

0.013

  Obese (n = 122)

−0.015 (−0.013 to 0.011)

0.871

−0.015 (−0.014 to 0.012)

0.883

Non-obese

  Non-hypertention (n = 79)

0.189 (−0.003 to 0.036)

0.091

0.171 (−0.005 to 0.036)

0.147

  Hypertension (n = 42)

0.357 (0.004 to 0.039)

0.019

0.190 (−0.010 to 0.032)

0.272

Obese

  Non-hypertention (n = 67)

−0.004 (−0.017 to 0.017)

0.978

0.042 (−0.016 to 0.021)

0.766

  Hypertension (n = 55)

−0.042 (−0.021 to 0.015)

0.771

−0.095 (−0.028 to 0.016)

0.588

  1. ADMA asymmetric dimethylarginine, BMI body mass index, CI confidential interval, GFR glomerular filtration rate, Hb hemoglobin, HDL high-density lipoprotein, RAS renin–angiotensin system
  2. aMultivariate models were adjusted for age, male sex, BMI, current smoking, diabetes duration, HbA1c, diabetic nephropathy stage, eGFR, high systemic blood pressure (≥140 mmHg), high triglyceride (≥150 mg/dl), low HDL-cholesterol (<40 mg/dl), medication of oral hypoglycemic agents, RAS inhibitors, diuretics, and statins
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