Table 2 Correlation analysis of clinical values and the relative abundance of core gut microbiota

		o_Lactobacillales	f_Alcaligenaceae	g_Eubacterium_hallii_group	g_Blautia	g_Faecalibacterium	g_Lachnoclostridium	g_Ruminococcus_2	s_Ruminococcus_sp._5_1_39BFAA	s_Escherichia_coli
FBG	r	0.553**	−0.149	0.260	0.249	−0.067	0.119	0.089	0.249	0.110
FBG	p	0.000	0.273	0.053	0.064	0.622	0.384	0.515	0.064	0.420
BUN	r	0.109	−0.225	0.281*	0.297*	−0.309*	−0.027	0.277*	0.312*	0.239
BUN	p	0.426	0.095	0.036	0.026	0.021	0.842	0.039	0.019	0.076
Scr	r	−0.011	−0.111	0.121	0.085	−0.137	0.030	0.320*	0.106	0.061
Scr	p	0.934	0.415	0.373	0.533	0.313	0.825	0.016	0.436	0.653
CRP	r	0.385**	−0.294*	0.296*	0.268*	−0.126	−0.048	0.018	0.245	0.148
CRP	p	0.003	0.028	0.027	0.046	0.355	0.726	0.895	0.068	0.276
HbA1c	r	0.325*	−0.121	0.086	0.101	0.015	0.047	−0.115	0.103	-0.025
HbA1c	p	0.015	0.373	0.526	0.457	0.910	0.729	0.399	0.448	0.855
Peak VO2/Kg	r	−0.284*	0.318*	−0.263	−0.290*	0.159	−0.143	−0.182	-0.273*	-0.355**
Peak VO2/Kg	p	0.034	0.017	0.050	0.030	0.241	0.293	0.181	0.042	0.007
VO2/Kg at AT	r	0.004	0.114	−0.123	−0.112	0.067	−0.050	−0.023	-0.068	-0.364**
VO2/Kg at AT	p	0.975	0.404	0.366	0.412	0.623	0.714	0.868	0.621	0.006
BMI	r	0.371**	−0.249	0.273*	0.242	−0.099	0.065	0.212	0.273*	0.123
BMI	p	0.005	0.066	0.044	0.074	0.474	0.637	0.120	0.044	0.373
SBP	r	−0.128	−0.073	−0.023	−0.003	0.136	0.158	−0.010	0.009	-0.253
SBP	p	0.353	0.598	0.869	0.982	0.322	0.248	0.942	0.947	0.063
DBP	r	−0.050	0.048	−0.130	−0.051	0.014	0.038	−0.132	-0.035	-0.080
DBP	p	0.718	0.726	0.345	0.713	0.922	0.784	0.338	0.802	0.562
Age	r	0.180	−0.119	0.085	0.070	0.001	0.268*	0.221	0.110	0.064
Age	p	0.185	0.382	0.533	0.608	0.992	0.046	0.101	0.418	0.640

Note: Spearman rank correlation was used to evaluate statistical importance: r: correlation coefficient
FBG fasting blood glucose, BUN blood urea nitrogen, Scr serum creatinine, CRP C-reactive protein, HbA1c hemoglobin A1C, Peak VO2 peak oxygen uptake, AT anaerobic threshold, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure
*p < 0.05, **p < 0.01

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