Table 3 BP levels at baseline and responses to dietary intervention by MAP GRS quartile

From: Association of Kir genes with blood pressure responses to dietary sodium intervention: the GenSalt study

 

Quartile 1

Quartile 2

Quartile 3

Quartile 4

Ptrend*

Baseline

SBP

116.5 (115.1, 118.0)

116.6 (115.3, 118.0)

117.1 (116.0, 118.2)

118.0 (116.8, 119.1)

0.11

DBP

73.54 (72.54, 74.54)

73.38 (72.38, 74.37)

73.79 (73.03, 74.54)

74.15 (73.30, 74.99)

0.30

MAP

87.86 (86.81, 88.92)

87.78 (86.76, 88.80)

88.20 (87.40, 89.01)

88.74 (87.88, 89.61)

0.17

Low-sodium intervention

SBP

−4.51 (−5.16, −3.85)

−5.06 (−5.71, −4.42)

−5.49 (−6.07, −4.90)

−6.59 (−7.21, −5.97)

2.59 × 10−6

DBP

−2.37 (−2.93, −1.80)

−2.51 (−3.08, −1.94)

−2.96 (−3.42, −2.50)

−3.22 (−3.73, −2.71)

0.01

MAP

−3.08 (−3.60, −2.55)

−3.36 (−3.88, −2.85)

−3.80 (−4.25, −3.36)

−4.34 (−4.83, −3.86)

1.94 × 10−4

High-sodium intervention

SBP

3.83 (3.26, 4.40)

4.92 (4.29, 5.55)

4.74 (4.21, 5.26)

5.74 (5.23, 6.25)

1.86 × 10−6

DBP

1.62 (1.07, 2.17)

2.17 (1.59, 2.75)

1.76 (1.26, 2.27)

2.35 (1.87, 2.83)

0.03

MAP

2.34 (1.84, 2.84)

3.08 (2.56, 3.61)

2.75 (2.29, 3.21)

3.49 (3.06, 3.92)

9.13 × 10−4

  1. Data are mean (95% CI). BP blood pressure, CI confidence interval, DBP diastolic blood pressure, GRS genetic risk score, MAP mean arterial pressure, P, P values, SBP systolic blood pressure. Age, gender, body mass index (BMI), and 24-hour urinary sodium were adjusted. * Linear trend between BP and GRS was calculated in the mixed effect model after adjusted the age, gender, BMI, and 24-h urinary sodium
Back to article page