Fig. 5
From: Renal nerves contribute to hypertension in Schlager BPH/2J mice
Average mean arterial pressure (MAP) responses to enalaprilat a, b and pentolinium c, d administration after pre-treatment with enalaprilat during the dark active period (left panels) or light inactive period (right panels) 2 weeks after renal denervation (RD, filled symbol) or sham surgery (open symbol) in genetically hypertensive BPH/2J (squares) and normotensive BPN/3J mice (circles). Histograms are mean change ± SEM from control period in BPN/3J sham mice (Grey unfilled, n = 10–11) and BPN/3J RD (grey filled, n = 6–7), BPH/2J sham (black unfilled, n = 8), BPH RD (black filled, n = 10) and were analysed by split plot analysis of variance. A probability of P < 0.05 was considered significant. *P < 0.05, **P < 0.01 and ***P < 0.001 for comparison of sham treatment with RD
