Table 2 Average mean arterial pressure, heart rate and power spectral parameters during the active (dark) period in normotensive (BPN/3J) and genetically hypertensive (BPH/2J) mice given either sham or renal denervation (RD)
From: Renal nerves contribute to hypertension in Schlager BPH/2J mice
Spectral analysis during the night (active) period | ||||||||
|---|---|---|---|---|---|---|---|---|
BPN Sham | BPH Sham | BPN Rx | BPH Rx | Sham BPN vs BPH | RD BPN vs BPH | BPN Sham vs RD | BPH Sham vs RD | |
MAP (mmHg) | 103.2 ± 1.9 | 128.8 ± 2.6 | 100.8 ± 2.3 | 117.3 ± 2.8 | < 0.001 | < 0.001 | >0.5 | 0.01 |
HR (beats/min) | 418 ± 12 | 529 ± 20 | 429 ± 16 | 522 ± 21 | < 0.001 | 0.001 | >0.5 | >0.5 |
MAP power (mmHg) 2 | ||||||||
Low frequency (0.08–0.3 Hz) | 3.08 ± 0.57 | 3.06 ± 0.52 | 4.16 ± 0.62 | 3.09 ± 0.58 | >0.5 | 0.35 | 0.29 | >0.5 |
Mid frequency (0.3–0.5 Hz) | 0.95 ± 0.2 | 2.05 ± 0.43 | 1.17 ± 0.29 | 1.85 ± 0.57 | 0.01 | 0.24 | >0.5 | >0.5 |
High frequency (0.5–3 Hz) | 0.27 ± 0.05 | 0.94 ± 0.25 | 0.47 ± 0.12 | 0.67 ± 0.19 | 0.003 | >0.5 | >0.5 | 0.36 |
Total | 8.26 ± 1.72 | 9.81 ± 1.70 | 9.29 ± 1.54 | 8.98 ± 1.90 | >0.5 | >0.5 | >0.5 | >0.5 |
HR power (beats/min) 2 | ||||||||
Low frequency (0.08–0.3 Hz) | 246.5 ± 43.8 | 321.8 ± 49.9 | 330.1 ± 66.3 | 160.5 ± 18.8 | 0.41 | 0.03 | 0.33 | 0.04 |
Mid frequency (0.3–0.5 Hz) | 141.8 ± 26.8 | 327.5 ± 64.9 | 206.8 ± 53.1 | 129.7 ± 34.1 | 0.01 | 0.48 | >0.5 | 0.01 |
High frequency (0.5–3 Hz) | 77.7 ± 18.3 | 180 ± 45.4 | 152.2 ± 51.7 | 71.3 ± 14.9 | 0.04 | 0.15 | 0.16 | 0.04 |
Total | 1162 ± 280 | 2599 ± 794 | 2063 ± 754 | 792 ± 122 | 0.04 | 0.11 | 0.26 | 0.02 |
Coherence (0.3–0.5 Hz) | 0.57 ± 0.01 | 0.59 ± 0.02 | 0.61 ± 0.01 | 0.58 ± 0.01 | >0.5 | >0.5 | 0.22 | >0.5 |
Gain (0.5–3 Hz) | 10.62 ± 0.73 | 12.0 ± 1.23 | 11.46 ± 0.89 | 8.77 ± 1.0 | >0.5 | 0.13 | >0.5 | 0.06 |
