Table 1 Comparison of the two types of primary aldosteronism : IHA and PA

From: Microvascular and macrovascular endothelial function in two different types of primary aldosteronism

 

IHA compared with EHT

APA compared with EHT

Plasma PAC level

Moderately increased

Greatly increased

Log RHI and FMD

Only log RHI decreased

Both log RHI and FMD decreased

Impaired vascular bed size

Microvascular endothelium

Micro- and macro-vascular endothelium

First-line treatment

Mineralocorticoid receptor antagonists and renin-angiotensin aldosterone inhibitors

Surgical resection of the adrenal adenoma

  1. APA aldosterone-producing adenoma, EHT essential hypertension, FMD flow-mediated dilation, IHA idiopathic hyperaldosteronism, PAC plasma aldosterone concentration, RHI reactive hyperemic index
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