Table 4 Orthostatic blood pressure reduction mediates the association between end-stage renal disease and memory deficit

From: Orthostatic blood pressure reduction as a possible explanation for memory deficits in dialysis patients

 

Estimate

95% CI

p

Short recall memory

 ACME

−0.20

−0.43 to −0.01

0.040

 ADE

−1.23

−1.91 to −0.55

<0.001

 Total effect

−1.43

−2.04 to −0.77

<0.001

 Proportion mediated

13.8%

0.6%–37.0%

0.040

Delayed recall memory

 ACME

−0.18

−0.41–0.01

0.07

 ADE

−1.94

−2.62 to −1.22

<0.001

 Total effect

−2.12

−2.79 to −1.45

<0.001

 Proportion mediated

8.7%

−0.7%–22.0%

0.07

  1. ACME average causal mediation effects, ADE average direct effect