Fig. 2 | Hypertension Research

Fig. 2

From: Resveratrol improves endothelial cell markers impaired by plasma incubation from women who subsequently develop preeclampsia

Fig. 2

Relative expression of the genes NFE2L2 (a), HMOX1 (b), and GSR (c) in HUVECs. HUVECs were incubated with 10% (v/v) plasma samples from pregnant women who subsequently developed preeclampsia (case) and who remained healthy during gestation (control) (n = 6 per group) for 24 h in the absence (−R) and presence of trans-resveratrol (+R) at 1 μM. Resveratrol significantly decreased GSR expression in the control group. HMOX1 and GSR expression was higher in the case group with resveratrol than in the controls with the same treatment. DMSO was used as a vehicle for trans-resveratrol. Values were normalized using HPRT1 as an endogenous control. Values are expressed as the mean ± S.E.M. #p ≤ 0.05 vs. respective group –R; †p ≤ 0.05 vs. control group+R

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