Fig. 1 | Hypertension Research

Fig. 1

From: Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1)

Fig. 1

Blood pressure, heart rate and home-cage activity in telemetered salt-inducible kinase 1 (SIK1) knockout (sik1−/−) and wild-type (sik1+/+) littermate mice challenged either a high-salt (8% NaCl) or control (0.3% NaCl) diet for 7 days. (a) Systolic blood pressure (SBP), (b) diastolic blood pressure (DBP), (c) mean arterial pressure (MAP), (d) heart rate (HR) and (e) home-cage activity. Mean ± SEM; n = 6–9 per group; values were determined to be significantly different from sik1+/+ mice (*P < 0.05) or control diet-fed counterparts (#P < 0.05) group by one-way analysis of variance followed by Fisher’s least significant difference (LSD) test

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