Table 2 Serum renin, angiotensin II and aldosterone levels after 1 week of 0.3 or 8% NaCl intake in sik1+/+ and sik1−/− mice

From: Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1)

 

0.3% NaCl diet

8% NaCl diet

 

sik1 +/+

sik1 −/−

sik1 +/+

sik1 −/−

Renin

465 ± 22

463 ± 18

462 ± 33

463 ± 32

Angiotensin II

33 ± 7

46 ± 10

44 ± 7

39 ± 9

Aldosterone

267 ± 67

197 ± 30

83 ± 9#

78 ± 6#

  1. All = pg/ml. Mean ± SEM, n = 3–6 per group. #P < 0.05 as compared with 0.3% NaCl feeding counterparts
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