Table 3 Tissue catecholamine levels after 1 week of 0.3 or 8% NaCl intake in sik1+/+ and sik1−/− mice

From: Acute salt loading induces sympathetic nervous system overdrive in mice lacking salt-inducible kinase 1 (SIK1)

 

0.3% NaCl diet

8% NaCl diet

 

sik1 +/+

sik1 −/−

sik1 +/+

sik1 −/−

Kidney

  Noradrenaline

2291 ± 195

2653 ± 222

2603 ± 137

2878 ± 232

  Dopamine

423 ± 43

381 ± 42

331 ± 11

351 ± 58

Ventricles

  Noradrenaline

2962 ± 183

2559 ± 161

2765 ± 163

2629 ± 240

  Dopamine

217 ± 18

169 ± 8

175 ± 7

153 ± 15

Atria

  Noradrenaline

6590 ± 673

7017 ± 1026

7047 ± 625

7474 ± 728

  Dopamine

833 ± 121

754 ± 73

746 ± 38

836 ± 102

Aorta

  Noradrenaline

6799 ± 992

8128 ± 971

8215 ± 490

9337 ± 1933

  Dopamine

681 ± 62

661 ± 55

799 ± 73

727 ± 112

  1. All = pmol/g tissue. Mean ± SEM, n = 5 per group
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