Table 2 Hazard ratios (HRs) and 95% confidence intervals (CIs) of cardiovascular events in different BP groups

From: Stage 1 hypertension defined by the 2017 ACC/AHA Hypertension Guidelines and Risk of Cardiovascular Events: a Cohort Study from Northern China

BP of 2006–2007

Normal BP

Elevated BP

Stage 1 HT

Stage 2 HT

P for trend

Cardiovascular events

 No. of cases

427

207

1135

3781

 

 Incidence rate/1000 person-years

2.24

3.93

3.89

9.75

 

 Modela

Reference

1.19 (1.01–1.42)*

1.25 (1.11–1.40)

2.30 (2.07–2.56)

 <0.001

 Modela,b

Reference

1.18 (0.99–1.40)

1.22 (1.09–1.37)

2.05 (1.84–2.29)

 <0.001

Myocardial infarction

 No. of cases

124

47

278

869

 

 Incidence rate/1000 person-years

0.65

0.88

0.94

2.18

 

 Modela

Reference

0.86 (0.61–1.23)

1.04 (0.83–1.29)

1.66 (1.35–2.03)

 <0.001

 Modela,b

Reference

0.85 (0.60–1.21)

1.01 (0.81–1.26)

1.50 (1.22–1.85)

 <0.001

Cerebral infarction

 No. of cases

254

138

724

2430

 

 Incidence rate/1000 person-years

1.33

2.60

2.46

6.17

 

 Modela

Reference

1.32 (1.06–1.63)*

1.31 (1.13–1.52)

2.44 (2.12–2.79)

 <0.001

 Modela,b

Reference

1.30 (1.05–1.61)*

1.28 (1.11–1.49)

2.18 (1.90–2.51)

 <0.001

Cerebral hemorrhage

 No. of cases

61

27

181

681

 

 Incidence rate/1000 person-years

0.32

0.50

0.61

1.70

 

 Modela

Reference

1.28 (0.81–2.03)

1.45 (1.07–1.97)*

3.26 (2.47–4.31)

 <0.001

 Modela,b

Reference

1.26 (0.80–2.00)

1.44 (1.06–1.94)*

2.83 (2.12–3.77)

 <0.001

  1. HT hypertension, BP blood pressure
  2. Compared with reference group, *P < 0.05, P < 0.01, or P < 0.001
  3. aAdjusted for age (yrs), sex, smoking (never and past, current, ≥1 cigarettes/d), alcohol drinking (never and past, current, ≥1 times/d), exercise (none, occasionally or frequently, ≥1 times/wk), education level (elementary school, high school or above), income level (<1000 yuan/month and ≥1000 yuan/month), body mass index, fasting blood glucose, total cholesterol, uric acid, and high-sensitivity C-reactive protein
  4. bExcluding 9598 participants who were taking antihypertensive drugs