Fig. 1
From: Azilsartan causes natriuresis due to its sympatholytic action in kidney disease

Body weight, urinary volume, serum creatinine concentration, and urinary protein excretion in the three groups. a Body weight was significantly lower in the VEH and AZ groups (**P < 0.001 sham vs. VEH and AZ). b The urinary volume was significantly higher in the VEH and AZ groups (**P < 0.001 sham vs. VEH and AZ). c The serum creatinine concentration was significantly higher after adenine administration (**P < 0.001 sham vs. VEH and AZ). Although there was no significant difference in the VEH and AZ groups at 5 weeks, the serum creatinine concentration was significantly lower in the AZ group than in the VEH group (†P < 0.05 AZ vs. VEH). d Urinary protein excretion was also significantly higher after adenine administration (**P < 0.001 sham vs. VEH and AZ). Though there was no significant difference between the VEH and AZ groups at 9 weeks, urinary protein excretion tended to be suppressed from 5 to 9 weeks in the AZ group (P = 0.10)