Table 3 Odds ratio of BP levels at 8–11 weeks of gestation, pre-pregnancy BMI, primiparity, age, past history of GH/PE, and multiple pregnancy for the occurrence of GH
Risk factors | Number of risk factors | GH numbers (frequency) | Incidence of GH | |||
---|---|---|---|---|---|---|
cOR | (95% CI) | aOR | (95% CI) | |||
BP levels at 8–11 weeks | ||||||
Normal BP | 2258 | 8 (0.4) | 1 | 1 | ||
High-normal BP | 263 | 5 (1.9) | 5.5 (1.8–16.8) | 5.5 (1.8–17.4) | ||
High BP or THT | 193 | 17 (8.8) | 27.3 (11.6–64.1) | 27.6 (11.1–68.5) | ||
WCH | 18 | 6 (33.3) | 141 (42.5–469) | 160 (40.5–632) | ||
Pre-pregnancy BMI | ||||||
<25.0 | 2259 | 22 (1.0) | 1 | 1 | ||
25.0–29.9 | 306 | 7 (2.3) | 2.4 (1.01–5.6) | 0.79 (0.313–2.0) | ||
≥30.0 | 175 | 7 (4.0) | 4.2 (1.8–10.1) | 0.71 (0.25–2.0) | ||
Parity | ||||||
Multiparity | 1366 | 14 (1.0) | 1 | 1 | ||
Primiparity | 1,374 | 22 (1.6) | 1.6 (0.80–3.1) | 1.5 (0.68–3.2) | ||
Age | ||||||
Age <40 yr | 2436 | 29 (1.2) | 1 | 1 | ||
Age ≥40 yr | 304 | 7 (2.3) | 2.0 (0.85–4.5) | 1.4 (0.55–3.5) | ||
Past history of GH/PE | ||||||
Absence | 2673 | 33 (1.2) | 1 | 1 | ||
Presence | 67 | 3 (4.5) | 3.8 (1.12–12.5) | 2 (0.49–8.1) | ||
Multiple pregnancy | ||||||
Singleton pregnancy | 2571 | 34 (1.3) | 1 | 1 | ||
Twins or Triplets | 169 | 2 (1.2) | 0.89 (0.21–3.8) | 0.93 (0.20–4.3) |