Table 1 Clinical, metabolic, and inflammatory variables characterizing the cardiovascular risk profile in the whole sample at baseline and after 1 year

From: Traditional cardiovascular risk factors and residual disease activity are associated with atherosclerosis progression in rheumatoid arthritis patients

 

Baseline (n = 137)

Follow-up (n = 105)

p value

CV risk factors

  BMI, kg/m2

25.08 ± 3.88

25.09 ± 3.98

N.s.

  Smoke, (%)

40

39

N.s.

  Hypertension, (%)

48.6

54.2

0.045

  Dyslipidaemia, (%)

68.6

67.6

N.s.

  Diabetes, (%)

6.7

6.7

N.s.

  Systolic BP (mmHg)

136.5 ± 17.7

134.9 ± 16.4

N.s.

  Diastolic BP (mmHg)

83.4 ± 9.1

81.1 ± 9.7

N.s.

  Fasting glycaemia, mg/dl

90.96 ± 24.59

89.88 ± 22.01

N.s.

  Total cholesterol, mg/dl

215.15 ± 38.08

209.14 ± 46.00

N.s.

  LDL, mg/dl

120.28 ± 33.97

120.17 ± 35.36

N.s.

  HDL, mg/dl

69.52 ± 18.92

69.34 ± 18.58

N.s.

  Triglycerides, mg/dl

121.88 ± 61.85

113.86 ± 55.22

N.s.

RA characteristics

  CRP, mg/l

4.19 ± 8.43

3.96 ± 6.61

N.s.

  DAS28 [CRP]

2.65 ± 1.08

2.77 ± 1.33

N.s.

  Disease duration at baseline, years

15.45 ± 10.57

RA treatments

  csDMARDs, %

76.6

72.9

N.s.

  Methotrexate, %

53.3

45.8

  Leflunomide, %

17.8

18.7

  Hydroxychloroquine, %

12.1

11.2

  bDMARDs, %

74.8

70.1

N.s.

  TNFi, %

45.8

40.2

  Tocilizumab, %

11.2

11.2

  Rituximab, %

5.6

4.7

  Abatacept, %

9.3

13.1

  Corticosteroids, %

66.4

57.9

0.028

  NSAIDs, %

20.6

21.5

N.s.

  1. BMI body mass index, BP blood pressure, LDL low-density lipoproteins, HDL high-density lipoproteins, CRP c-reactive protein, DAS28 disease activity score, DMARDs disease modifying drugs, NSAID nonsteroidal anti-inflammatory drugs, N.s. not significant