Table 4 Enhancement in prediction of adult cardiovascular risk by times abnormal BP was observed during childhood when aged 6–18 years

From: The predictive value of repeated blood pressure measurements in childhood for cardiovascular risk in adults: the Hanzhong Adolescent Hypertension Study

Cardiovascular risk

Abnormal BP

observed in childhood

AUC

(unadjusted model)

P for AUC

difference

AUC

(multivariable-adjusted model)a

P for AUC

difference

Adult hypertension

 

Once

0.568 (0.545–0.592)

Ref

0.697 (0.675–0.719)

Ref

 

Twice

0.586 (0.562–0.609)

0.1012

0.766 (0.745–0.786)

<0.0001

 

Three times

0.556 (0.532–0.580)

0.4357

0.692 (0.669–0.713)

0.4777

Adult AS

 

Once

0.537 (0.513–0.560)

Ref

0.702 (0.680–0.724)

Ref

 

Twice

0.564 (0.541–0.588)

0.0045

0.708 (0.686–0.729)

0.3997

 

Three times

0.537 (0.514–0.561)

0.9706

0.697 (0.674–0.718)

0.2780

Adult LVH

 

Once

0.575 (0.549–0.601)

Ref

0.611 (0.585–0.636)

Ref

 

Twice

0.576 (0.550–0.602)

0.9491

0.649 (0.624–0.674)

0.1722

 

Three times

0.524 (0.498–0.550)

0.1020

0.587 (0.561–0.613)

0.4487

  1. AS arterial stiffness, LVH left ventricular hypertrophy
  2. aMultivariable-adjusted model was adjusted for age, sex, family history of hypertension, heart rate, and height at baseline for once; adjusted for age, sex, family history of hypertension, heart rate at baseline, and weight at follow-up for twice; adjusted for age, sex, family history of hypertension, heart rate, and body mass index at baseline for three times
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