Table 3 Characteristics of ongoing clinical trials for studying the safety and efficacy of ARBs and ACEI in patients with COVID-19
From: Understanding the role of nACE2 in neurogenic hypertension among COVID-19 patients
Drug | Design | Status | Group | Total number | Primary outcome | Country of registration |
|---|---|---|---|---|---|---|
ACEI/ARB | Interventional | Enrolling by invitation | ACEI /ARB | 152 | Clinical status -Severity of disease, admission to ICU, Death | USANCT04338009 |
ACEI/ARB | Observational | Not yet recruiting | ACEI/ARB | 6000000 | Clinical status-identification of disease severity | France NCT04356417 |
ACEI/ARB | Interventional | Recruiting | ACEI/ARB | 208 | Clinical status- Severity of disease, admission to ICU, Death | Austria NCT04353596 |
ACEI/ARB | Observational | completed | ACEI/ARB | 314 | Clinical status-Severity of disease, admission to ICU, Death | Saudi Arabia NCT04357535 |
ARB, ACEi, DRi | Observational | Recruiting | ARB, ACEi, DRi | 10 | Clinical status-Severity of disease and BP | Ukraine NCT04364984 |
ACEI/ARB | Observational | Completed | ACEI/ARB And Non-ACEI/ARB | 10000 | Clinical status-Hospitalization and mortality | USA NCT04467931 |
ACEI/ARB | Interventional | Recruiting | ACEI/ARB | 215 | Clinical status-Admission to hospital and death | Denmark NCT04351581 |
ACEI/ARB | Observational | Recruiting | ACEI/ARB | 2574 | Hospital output-Clinical status | Spain NCT04367883 |
ACEI/ARB | Interventional | Recruiting | ACEI/ARB | 700 | Clinical status- admission to ICU and death | Brazil NCT04364893 |
ACEI/ARB and Non-ARB/ACEI | Interventional | Suspended | ACEI/ARB and Non-ARB/ACEI | 2414 | Clinical status- Severity of disease, admission to ICU | Ireland NCT04330300 |
ACEI/ARB | Observational | Recruiting | ACEI/ARB | 500 | Clinical status- Severity of disease, admission to ICU, Death | Canada NCT04510623 |
ACEI/ARB | Observational | Completed | ACEI/ARB | 275 | Rate of death | China NCT04318301 |
ACEI/ARB | Observational | Not yet Recruiting | ACEI/ARB | 5000 | Disease severity or death | Italy NCT04318418 |
ACEI/ARB | Interventional | Recruiting | ACEI/ARB | 554 | Clinical status- clinical improvement of Patients | France NCT04329195 |
ACEI/ARB | Observational | Recruiting | ACEI/ARB | 2000 | Clinical status of patients | Italy NCT04331574 |
ACEI/ARB | Interventional | Recruiting | ACEI/ARB | 240 | Disease severity, ICU, and Clinical status | Brazil NCT04493359 |
