Table 1 Demographics, blood pressure profiles, treatments and outcomes of patients

From: Therapeutic target and clinical impact of day-to-day blood pressure variability in hypertensive patients with covid-19

 

Controlled Hypertension

(n = 115)

Uncontrolled Hypertension

(n = 236)

P value

Non-Severe Covid-19

(n = 137)

Severe covid-19

(n = 214)

P value

Demographics

  Age, year

52 ± 17

55 ± 26

0.473

50 ± 27

56 ± 30

0.053

  Sex, men

41.2%

58.8%

0.033

51.2%

49.9%

0.231

BP on admission

  SBP, mmHg

126 ± 18

144 ± 31

0.007

128 ± 10

130 ± 22

0.144

  DBP, mmHg

81 ± 11

92 ± 18

0.043

80 ± 9

80 ± 15

0.556

  MAP, mmHg

96 ± 13

97 ± 16

0.632

99 ± 20

97 ± 23

0.473

Comobidities

  Diabetes mellitus

32.9%

25.6%

0.063

14.6%

34.5%

0.003

  CAD

32.9%

17.6%

0.556

32.9%

27.6%

0.556

  CKD

14.1%

33.3%

0.188

14.1%

33.3%

0.188

  Heart failure

10.6%

17.6%

0.631

10.6%

17.6%

0.631

Antihypertensive drugs on admission

  AdCEis/ARBs

60.5%

64.2%

0.152

60%

62.3%

0.209

  Beta blockers

18.5%

25%

0.131

25.2%

22.3%

0.440

  CCBs

42%

43.1%

0.665

44.5%

46.8%

0.556

  Diuretics

22.3%

19.3%

0.154

23.1%

18,3%

0.188

  Any of drugs above

12.3%

27.9%

0.045

33.4%

27%

0.052

Other medications

  Glucocorticoid

86.9%

83.8%

0.822

87.5%

92.5%

0.082

  Anticoagulant

52.1%

55.1%

0.898

36.49%

84.1%

0.000

BP Profile during hospitalization

  MAPCV

2.1 ± 2.85

3.27 ± 4.9

0.002

2.9 ± 3.77

1.88 ± 2.42

0.000

  High BPV

40.2%

59.8%

0.003

68.4%

31.6%

0.005

Outcome

  In-hospital mortality

16.52%

46.08%

0.003

8.02%

37.8%

0.000

  1. ABP blood pressure, SBP systolic blood pressure, DBP diastolic blood pressure, MAP mean arterial pressure, CAD coronary artery disease, CKD chronic kidney disease, ACEis angiotensin converting enzyme inhibitors, ARBs angiotensin receptor blockers, CCBs calcium channel blockers, MAPCV mean arterial pressure coefficient of variation, BPV blood pressure variability