Fig. 2 | Hypertension Research

Fig. 2

From: Sodium glucose cotransporter 2 inhibitor suppresses renal injury in rats with renal congestion

Fig. 2

Histological analysis of renal injury and fibrosis in the cortex of rats with IVC ligation. A Representative light micrographs of Elastica-Masson (EM) staining and immunohistochemical staining for markers of fibrosis and tubular damage in the cortex. Scale bar = 100 µm. B Quantification of positively stained area of EM staining and immunohistochemical staining using ImageJ. Data are presented as individual values and mean ± SEM; n = 12 per group. *P < 0.05, **P < 0.01, ***P < 0.001, ns not significant (P > 0.05) by Steel-Dwass test. R, right kidney; L, left kidney; CMC, rats without tofogliflozin treatment; Tofo, rats with tofogliflozin treatment

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