Fig. 1
From: The role of SARS-CoV-2-mediated NF-κB activation in COVID-19 patients
The canonical and non-canonical NF-κB activation signaling pathway. In the canonical NF-κB activation pathway, IKKβ and IKKγ are required and the NF-κB dimers are usually p65/p50 or p50/c-Rel dimers. In the non-canonical NF-κB activation pathway, however, phosphorylation of NIK and activation of IKKα are required, and the NF-κB dimers are usually RelB/p52 dimer
