Table 6 The effect of interventions on serum adrenocorticotropic hormone (ACTH) and cortisol

From: A study on the early metabolic effects of salt and fructose consumption: the protective role of water

 

Length of follow-up

p*

p†

Baseline

120 min

Cortisol, mcg/dL

 Group 1

18.1 (15.9–20.2)

27.3 (25.2–29.5)

<0.001

<0.001

 Group 2

17.5 (15.4–19.7)

19.4 (17.3-21.6)

 Group 3

18.6 (16.4–20.7)

25.4 (23.3–27.6)

 Group 4

19.3 (17.2–21.4)

22.1 (19.9–24.3)

 p‡

0.71

<0.001

ACTH, pg/mL

 Group 1

21.2 (18.4–23.9)

27.9 (25.1–30.7)

<0.001

<0.001

 Group 2

17.1 (14.3–19.9)

20.1 (17.3–22.9)

 Group 3

20.1 (17.3–22.8)

27.1 (24.3–29.8)

 Group 4

21.6 (18.8–24.3)

20.8 (18.0–23.6)

 p‡

0.11

<0.001

  1. Data are presented as mean (95% CI) at baseline, and least-squares mean (95% CI) at 2 h
  2. Analysis was conducted using a mixed model for repeated measures, adjusting for baseline
  3. *p Value for time effect—trend over time in all arms
  4. †P Value for treatment × time interaction—evaluates if changes in one arm are different from the changes in the other arms
  5. ‡p Value for comparison between arms at each moment
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