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Prevalence of masked and white-coat hypertension among individuals with diabetes: insights from web-based home blood pressure monitoring in the Brazilian population

A Comment to this article was published on 07 November 2024

Abstract

The association between diabetes mellitus (DM) and masked hypertension (MH) in ambulatory blood pressure (BP) monitoring is established, but its relationship with home BP monitoring (HBPM) remains uncertain. This web-based database study compared BP phenotypes in individuals using (n = 51,194; 6.05% with DM) and not using (n = 55,320; 0.63% with DM) antihypertensive medications (AH) undergoing HBPM. Multivariable logistic regression analysis revealed similar MH and white-coat hypertension (WCH) prevalence in individuals with or without DM, irrespective of AH use. However, among AH non-users, DM was associated with a higher likelihood of normotension (OR 1.35, 95%CI 1.09–1.66; p = 0.006) and a lower likelihood of sustained hypertension (OR 0.77, 95%CI 0.60–0.99; p = 0.039) compared to individuals without DM. These findings suggest that while DM does not significantly impact MH and WCH in HBPM, it may influence normotension and sustained hypertension rates in AH non-users.

Likelihood of diabetes mellitus according to blood pressure phenotypes. AH – antihypertensive medications; CH – controlled hypertension; MH – masked hypertension; MUCH – masked uncontrolled hypertension; NT – normotension; SH – sustained hypertension; SUCH – sustained uncontrolled hypertension; WCH – white-coat hypertension; WUCH – white-coat uncontrolled hypertension.

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Correspondence to Audes D. M. Feitosa.

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ADMF, MAM-G, and WSB are consultants for Omron.

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Diniz, P.G.S., Bezerra, R., Feitosa, C.L. et al. Prevalence of masked and white-coat hypertension among individuals with diabetes: insights from web-based home blood pressure monitoring in the Brazilian population. Hypertens Res 47, 3473–3479 (2024). https://doi.org/10.1038/s41440-024-01842-0

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