Fig. 1

Changes from baseline to EOT in (A–D) morning home, (E, F) bedtime home, and (G, H) office BP (full analysis set). (A, C, E, G) ARB subgroup; (B, D, F, H) CCB subgroup. For (C and D), the red dotted line (3.9 mmHg) and blue dotted line (2.1 mmHg) indicate the non-inferiority criteria. Data are LS mean (95% CI) for panels A–D. Data are arithmetic mean (95% CI) for (E–H). ***p < 0.001 versus baseline, paired t-test. ARB angiotensin receptor blocker, BP blood pressure, CCB calcium channel blocker, CI confidence interval, DBP diastolic blood pressure, EOT end of treatment, LS least squares, SBP systolic blood pressure