Table 1 The characteristics of the participant in each group (n = 4396)

From: Impact of inter-twin growth discordance on preeclampsia: based on ultrasonic estimated fetal weight

Characteristics

Total 4396(100.0)

Normotensive, 3651(83.0)

GHa, 134(3.1)

PEb,611(13.9)

pc

Maternal age (years), n (%)

 ≀30

1558(35.4)

1344(36.8)

40(29.9)

174(28.5)

<0.001

 31–35

2050(46.6)

1682(46.1)

65(48.5)

303(49.6)

 >35

788(17.9)

625(17.1)

29(21.6)

134(21.9)

Gravidity, n (%)

 1

2315(52.7)

1909(52.3)

71(53.0)

335(54.8)

0.506

 β‰₯2

2081(47.3)

1742(47.7)

63(47.0)

276(45.2)

Parity, n (%)

 0

3672(83.5)

3023(82.8)

120(89.6)

529(86.6)

0.011

 β‰₯1

724(16.5)

628(17.2)

14(10.4)

82(13.4)

 ARTd, n (%)

2437(55.4)

1956(53.6)

81(60.5)

400(65.5)

<0.001

 GDMe, n (%)

858(19.5)

686(18.8)

38(28.4)

134(21.9)

0.006

Chronicity, n (%)

 DCf

3987(90.7)

3288(90.1)

129(96.3)

570(93.3)

0.003

 MCg

409(9.3)

363(9.9)

5(3.7)

41(6.7)

 GA at deliveryh, Mean ± SD

36.01 ± 1.80

36.06 ± 1.87

36.33 ± 1.13

35.60 ± 1.35

<0.001

 GA at delivery, Mean ± SD (in DC) i

36.25 ± 1.57

36.32 ± 1.63

36.39 ± 1.02

35.7 ± 1.22

<0.001

 GA at delivery, Mean ± SD (in MC) i

35.30 ± 1.80

35.36 ± 1.81

34.04 ± 1.20

34.86 ± 1.71

<0.001

 Birthweight Large, Mean ± SD

2493.72 ± 442.67

2504.93 ± 449.45

2542.56 ± 335.48

2416.02 ± 413.86

<0.001

 Birthweight Small, Mean ± SD

2433.27 ± 454.35

2453.79 ± 446.38

2443.36 ± 409.35

2308.41 ± 431.72

<0.001

 Pre-pregnancy BMI (kg/m2), Mean ± SD

22.39 ± 3.14

22.23 ± 3.02

23.75 ± 3.21

23.05 ± 3.61

<0.001

 Frequency of ultrasonic measurementj, (n = 15217)

 1

4396(28.9)

3651(28.8)

134(28.1)

611(29.5)

0.993

 2

3867(25.4)

3223(25.4)

122(25.5)

522(25.2)

 3

3331(21.9)

2784(22.0)

102(21.3)

445(21.5)

 4

2421(15.9)

2014(15.9)

77(16.1)

330(16.0)

 5

1202(7.9)

998(7.9)

43(9.0)

161(7.8)

Inter-twin growth discordance, Frequency (%)k (n = 15,217)

 10%

4779(31.4)

3862(30.5)

162(33.9)

755(36.5)

<0.001

 15%

2038(13.4)

1627(12.8)

69(14.4)

342(16.5)

<0.001

 20%

766(5.03)

621(4.9)

21(4.4)

124(6.0)

0.088

 Difference%, Mean ± SDj (n = 15,217)

8.06 ± 6.38

7.95 ± 6.32

8.21 ± 6.52

8.70 ± 6.71

0.002

 EFW_Largel, Mean ± SD (n = 15,217)

993.75 ± 685.87

995.48 ± 687.29

1003.30 ± 703.25

980.92 ± 673.16

0.774

 EFW_Small, Mean ± SD (n = 15,217)

925.57 ± 640.56

928.76 ± 643.33

931.38 ± 643.71

904.66 ± 622.50

0.981

  1. aGH: Gestational hypertension
  2. bPE: Preeclampsia
  3. cObtained through Pearson chi-square test in categorical variables and nonparametric test in continuous variables.
  4. dART: Assisted reproduction technologies
  5. eGDM: Gestational diabetes mellitus
  6. fDC: Dichorionic
  7. gMC: Monochorionic
  8. hGA: Gestational age
  9. iThe p values of nonparametric test between the comparison of GA at delivery in DC and MC groups were all below 0.001
  10. jThe frequency of positive events (inter-twin growth discordance) measured by ultrasound. Each individual may have multiple positive events during the whole pregnancy
  11. kIt was calculated by the formula: (the estimated fetal weight of the larger fetus)β€”(the estimated fetal weight of the smaller fetus)/(estimated fetal weight of the larger fetus) *100%
  12. lEFW: Estimated fetal weight