Table 3 Association between different degrees of inter-twin growth discordance and the risk for GH or PE in DC and MC twins (n = 4396)

From: Impact of inter-twin growth discordance on preeclampsia: based on ultrasonic estimated fetal weight

GH or PE

DC (n = 3987)

Β 

MC (n = 409)

10%

15%

20%

P for trend

10%

15%

20%

P for trend

ORb (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

GH or PE

1.261(1.134,1.403)

1.317(1.141,1.519)

1.212(0.962,1.528)

<0.001

2.297(1.430,3.690)

1.771(1.011,3.105)

0.985(0.415,2.337)

0.012

PE

1.285 (1.143,1.444)

1.356(1.111,1.540)

1.287(1.002,1.640)

<0.001

2.410(1.452,3.400)

1.909(1.064,3.426)

0.935(0.365,2.395)

0.012

Early PE

1.706(1.337,2.178)

2.085(1.553,2.801)

2.647(1.782,3.931)

<0.001

3.375(1.450,7.855)

2.981(1.309,6.788)

1.850(0.490,6.994)

0.004

Late PE

1.209(1.063,1.374)

1.219(1.025,1.450)

1.027(0.762,1.384)

0.044

1.965(1.053,3.669)

1.404(0.648,3.039)

0.491(0.134,1.797)

0.195

Mild PE

1.286(1.097,1.508)

1.349(1.094,1.664)

1.198(0.839,1.711)

0.052

2.695(1.272,5.711)

1.853(0.739,4.641)

0.435(0.081,2.339)

0.121

Severe PE

1.282(1.095,1.501)

1.356(1.102,1.670)

1.353(0.984,1.860)

<0.001

2.212(1.140,4.292)

1.935(0.943,3.971)

1.283(0.421,3.908)

0.035

  1. aGH: gestational hypertension, PE: preeclampsia, DC: Dichorionic group, MC: Monochorionic group
  2. bAdjusted for maternal age, gravidity, parity, pre-pregnancy BMI (kg/m2), gestational weeks at ultrasound measurement, the use of assisted reproduction technologies, and Gestational diabetes mellitus
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