Table 1 Demographics of the PA patients in the black, grey, and white groups

From: Speculating suitability of partial adrenalectomy for lateralized primary aldosteronism: With emphasis on partial and complete success as optimistic outcomes

 

Black (n = 63)

Grey (n = 79)

White (n = 63)

p-value

Mean age, years (SD)

48.4 (10.9)

50.6 (10.6)

54.2 (11.6)

0.0125

Males, n (%)

35 (55.6%)

36 (45.6%)

29 (46.0%)

0.433

Mean body weight, kg (SD)

69.0 (14.1)

69.2 (16.8)

69.0 (15.0)

0.9948

Mean body height, cm (SD)

165.7 (8.8)

164.1 (9.0)

163.5 (9.0)

0.3477

Mean BMI, kg/m2 (SD)

25.0 (4.0)

25.5 (4.5)

25.5 (3.9)

0.7223

Mean waist line, cm (SD)

84.9 (11.4)

85.6 (13.5)

84.9 (11.9)

0.931

Mean buttocks width, cm (SD)

96.8 (7.3)

97.1 (11.1)

96.8 (9.4)

0.9674

Mean blood pressure, mmHg (SD)

 Systolic

157.9 (22.7)

154.9 (19.4)

150.2 (19.0)

0.1059

 Diastolic

95.5 (14.2)

92.3 (12.3)

90.2 (13.5)

0.0869

Medical history, n (%)

 DM

4 (6.35%)

14 (17.72%)

10 (15.87%)

0.103

 Hyperlipidemia

11 (17.46%)

19 (24.05%)

18 (28.57%)

0.333

 Hyperthyroidism

0

1 (1.27%)

0

1

 Hypothyroidism

1 (1.59%)

0

2 (3.17%)

0.286

 Atrial fibrillation

2 (3.17%)

3 (3.80%)

1 (1.59%)

0.877

 CAD/MI

0

0

0

 

 CVA

4 (6.35%)

5 (6.33%)

4 (6.35%)

1

 Renal stone

6 (9.52%)

5 (6.33%)

3 (4.76%)

0.612

 Smoking history

7 (11.11%)

5 (6.33%)

11 (17.46%)

0.114

 Family history of HTN

35 (55.56%)

60 (75.95%)

44 (69.84%)

0.033

 Duration of HTN, year(s) (SD)

5.8 (6.6)

8.2 (7.1)

8.4 (8.7)

0.084

 CCI (SD)

1.5 (1.5)

1.5 (1.3)

1.5 (1.4)

0.9692

 AVS LI (SD)

4.61 (6.35)

5.44 (6.43)

2.91 (3.43)

0.3721

 Contralateral suppression, n (%)

3 (4.8%)

2 (2.53%)

0

0.277

 Maximum adrenal nodule diameter, cm (SD)

1.9 (1.2)

1.8 (1.1)

1.7 (0.7)

0.84

 Mean number of antihypertensive agents, n (SD)

2.0 (1.3)

2.2 (1.1)

1.9 (1.3)

0.3229

 ACEI, n (%)

2 (3.2%)

0

0

0.187

 α-blocker, n (%)

18 (28.6%)

16 (20.3%)

14 (22.2%)

0.491

 β-blocker, n (%)

22 (34.9%)

29 (36.7%)

23 (36.5%)

0.973

 ARB, n (%)

25 (4.0%)

39 (4.9%)

24 (3.8%)

0.331

 CCB, n (%)

39 (61.9%)

58 (73.4%)

39 (61.9%)

0.237

 Aldactone, n (%)

15 (2.4%)

23 (2.9%)

11 (1.7%)

0.27

 Vasodilator, n (%)

6 (9.5%)

5 (6.3%)

3 (4.8%)

0.612

 Diuretics, n (%)

2 (3.2%)

6 (7.6%)

7 (11.1%)

0.215

Pre-operative

 Mean serum potassium, mEq/L (SD)

3.5 (0.6)

3.6 (0.6)

3.9 (0.5)

0.0006

 Mean serum creatinine, mg/dL (SD)

0.9 (0.5)

0.9 (0.3)

0.9 (0.3)

0.5267

 Mean plasma aldosterone, ng/dl (SD)

57.0 (32.3)

60.5 (49.9)

42.4 (24.4)

0.0159

 Mean PRA, ng/ml/hr (SD)

0.5 (0.9)

0.5 (0.7)

0.5 (0.9)

0.7957

 Mean ARR (SD)

756.9 (1958.9)

1136.8(2425.1)

971.9 (2100.8)

0.5915

Post-operative 6th month

 Mean serum potassium, mEq/L (SD)

4.4 (0.5)

4.4 (0.4)

4.1 (0.4)

0.0006

 Mean serum creatinine, mg/dL (SD)

1.2 (0.7)

1.0 (0.4)

1.0 (0.5)

0.0755

 Mean plasma aldosterone, ng/dl (SD)

26.2 (19.5)

31.8 (21.8)

35.0 (23.3)

0.1022

 Mean PRA, ng/ml/hr (SD)

3.6 (3.0)

2.1 (2.2)

1.9 (3.0)

0.0023

 Mean ARR (SD)

48.3 (117.8)

94.3 (278.3)

196.1 (608.9)

0.118

Post-operative 12th month

 Mean serum potassium, mEq/L (SD)

4.3 (0.5)

4.3 (0.4)

4.2 (0.4)

0.113

 Mean serum creatinine, mg/dL (SD)

1.2 (0.9)

1.0 (0.4)

1.0 (1.0)

0.1545

 Mean plasma aldosterone, ng/dl (SD)

27.7 (20.1)

39.5 (25.2)

32.4 (16.1)

0.01

 Mean PRA, ng/ml/hr (SD)

3.3 (2.3)

3.5 (4.8)

2.2 (3.0)

0.1325

 Mean ARR (SD)

88.1 (443.9)

123.6 (425.7)

304.7 (1078.8)

0.2253

  1. PA primary aldosteronism, SD standard deviation, BMI body mass index, DM diabetes mellitus, CAD coronary artery disease, MI myocardial infarction, CVA cerebrovascular accident, HTN hypertension, CCI Charlson comorbidity index, AVS adrenal venous sampling, LI lateralization index, ACEI angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blockers, CCB calcium channel blockers, PRA plasma renin activity, ARR aldosterone-renin ratio